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Home Educational Resources Inhalers Advair® Diskus®
Advair® Diskus®

Advair® Diskus®

Generic Name: Fluticasone and Salmeterol


Advair® Diskus®

Instructions for use

  1. Wash and dry your hands well.
  2. Open the device.
  3. Hold device in a level, flat position. Do not shake this inhaler.
  4. Slide the lever from left to right until it clicks.
  5. Exhale out through mouth away from inhaler.
  6. Place the mouthpiece into your mouth and close your lips tightly around it.
  7. Keep the device level while inhaling the dose with a quick, deep breath.
  8. Remove the mouthpiece and hold breath for 10 seconds or as long as comfortable.
  9. Exhale through your mouth slowly and away from the inhaler.
  10. Close the inhaler.
  11. Rinse your mouth or brush your teeth after taking the dose and spit the water out — do not swallow.
  12. Store inhaler in a cool dry place.

Key product details

Medication Class and Use

  • Combination inhaler (maintenance inhaler, long-acting beta-2 agonist (LABA) and corticosteroid). This inhaler combines two medications that work over time to make breathing easier. Together the medications relax the muscles in the airway and decrease inflammation, swelling and mucus production.
  • Use this inhaler every day to prevent symptoms, even when feeling well.
  • Do not use for fast relief.
  • Do not use in combination with any other LABA containing medicine.


  • Available strengths: 100/50 mcg; 250/50 mcg; 500/50 mcg.
  • Usual COPD dosing: 250/50 mcg: 1 inhalation twice daily.
  • Asthma dosing in patients ≥12 years: 1 inhalation of 100/50, 250/50, or 500/50 twice daily. Starting dosage is based on asthma severity.
  • Asthma doing in patients aged 4 to 11 years: 1 inhalation of 100/50 twice daily.
  • Max recommended dose is 500/50 mcg twice daily.
  • Each inhaler contains 60 blisters (institutional pack = 14 blisters).


  • Inhaler is empty when dose counter reads 0 (doses 5-0 are red to remind getting a refill).


  • Wipe outside with dry tissue or cloth when needed. Do NOT wash any part of the inhaler. Keep dry.

Safety Information

  • Do not use in combination with any other long-acting beta2-adrenergic agonist (LABA) medicine for any reason.
  • People with asthma who take (LABA) medicines, such as salmeterol (one of the medicines in ADVAIR Diskus), have an increased risk of death from asthma problems. It is not known whether fluticasone propionate, the other medicine in ADVAIR Diskus, reduces the risk of death from asthma problems seen with salmeterol.


  1. Galvin WF, Dunn PJ, Kallstrom TJ. A Patient’s Guide to Aerosol Drug Delivery. American Association for Respiratory Care; 2010.
  2. Product Information: ADVAIR DISKUS inhalation powder, fluticasone propionate salmeterol inhalation powder. GlaxoSmithKline, Research Triangle Park, NC, 2016.

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The information provided is educational purposes only. It should not be used as a substitute for professional medical advice, diagnosis or treatment.

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